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Diagnosis and Treatment

Stages of UTUC
Stages of UTUC

Upper tract urothelial carcinoma (UTUC) is a rare cancer that affects the inner lining of the ureters or the renal pelvis (upper part of the kidney collecting system). Though less common than bladder cancer, UTUC requires early detection and experienced management.

At our urology clinic in Tbilisi, we provide accurate diagnosis, endoscopic evaluation, and both kidney-sparing and radical treatments for UTUC.


What Is UTUC?

UTUC arises from the urothelial lining of the renal pelvis or ureters — the same type of cells involved in bladder cancer. It may be low-grade or high-grade, and can be either non-invasive or invasive.


Who Is at Risk?

  • Age > 60 years

  • Smoking

  • Personal or family history of bladder cancer

  • Chronic inflammation or infections in the urinary tract

  • Exposure to chemicals or aristolochic acid (from certain herbal medicines)


Symptoms

  • Blood in the urine (hematuria) – most common and often painless

  • Flank pain or side/back discomfort

  • Recurrent urinary infections

  • Unexplained weight loss or fatigue (advanced cases)

Many cases are diagnosed during CT urography or after cystoscopy for hematuria.

Diagnosis

We offer complete evaluation:

  • CT urography – gold standard for imaging

  • Ureteroscopy with biopsy – direct visualization and tissue sampling

  • Urine cytology

  • Kidney function tests


Treatment Options

Treatment depends on tumor grade, size, location, and patient kidney function:

  • Kidney-sparing endoscopic resection – for small, low-grade tumors

  • Laser ablation via ureteroscopy

  • Radical nephroureterectomy – removal of kidney, ureter, and bladder cuff for high-grade/invasive tumors

  • Intracavitary therapy (e.g., BCG or mitomycin) via ureteral catheter

  • Systemic chemotherapy or immunotherapy – for advanced cases

  • Surveillance protocols – for low-risk disease

Our team specializes in minimally invasive and organ-preserving techniques, whenever safe and possible.

📞 If you’ve had blood in your urine or suspicious imaging, book a consultation: +995598257727. Early diagnosis can save your kidney — and your life.


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